Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 2/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962700 | 0.94 | WEE1 (0.43) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962797 | 0.93 | WEE1 (0.47) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962777 | 0.92 | WEE1 (0.46) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962912 | 0.91 | TBK1 (0.41) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962877 | 0.90 | WEE1 (0.44) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962727 | 0.90 | ALK (0.45) | WEE1ALKEHMT2SLC2A1PTK2 | |
| SCHEMBL30962694 | 0.90 | WEE1 (0.44) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962810 | 0.90 | WEE1 (0.44) | WEE1JAK2ALKEHMT2PTK2 | |
| SCHEMBL30962847 | 0.90 | TBK1 (0.42) | WEE1TBK1JAK2ALKEHMT2 | |
| SCHEMBL30962911 | 0.87 | WEE1 (0.48) | WEE1ALKEHMT2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |