Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962861 | 0.92 | ALK (0.41) | TBK1JAK2ALKSLC2A1PKMYT1 | |
| SCHEMBL30962632 | 0.90 | WEE1 (0.43) | TBK1JAK2ALKSLC2A1PKMYT1 | |
| SCHEMBL30962912 | 0.90 | TBK1 (0.41) | TBK1JAK2ALKSLC2A1PKMYT1 | |
| SCHEMBL30962911 | 0.88 | WEE1 (0.48) | ALKWEE1TNK2EHMT2MAP4K1 | |
| SCHEMBL30962698 | 0.88 | ALK (0.43) | TBK1JAK2ALKWEE1TNK2 | |
| SCHEMBL30962902 | 0.86 | WEE1 (0.41) | TBK1JAK2ALKWEE1EHMT2 | |
| SCHEMBL30962700 | 0.84 | WEE1 (0.43) | TBK1JAK2ALKWEE1TNK2 | |
| SCHEMBL30962797 | 0.83 | WEE1 (0.47) | TBK1JAK2ALKSLC2A1WEE1 | |
| SCHEMBL30962777 | 0.83 | WEE1 (0.46) | TBK1JAK2ALKSLC2A1WEE1 | |
| SCHEMBL30962716 | 0.83 | ALK (0.43) | TBK1JAK2ALKWEE1TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |