Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962746 | 0.96 | LCK (0.41) | TNK2LCKJAK3BTKPTK2 | |
| SCHEMBL30962853 | 0.93 | TNK2 (0.48) | TNK2LCKJAK3BTKPTK2 | |
| SCHEMBL30962929 | 0.91 | SRC (0.46) | TNK2LCKJAK3EGFRSRC | |
| SCHEMBL30962930 | 0.91 | SRC (0.46) | TNK2LCKJAK3EGFRSRC | |
| SCHEMBL30962895 | 0.89 | SRC (0.44) | LCKJAK3PTK2SCN9AEGFR | |
| SCHEMBL30962748 | 0.89 | SRC (0.44) | LCKJAK3PTK2SCN9AEGFR | |
| SCHEMBL30962854 | 0.88 | LCK (0.42) | TNK2LCKJAK3BTKPDE4A | |
| SCHEMBL30962665 | 0.86 | WEE1 (0.44) | TNK2LCKJAK3BTKPTK2 | |
| SCHEMBL30962757 | 0.86 | WEE1 (0.44) | TNK2LCKJAK3BTKPTK2 | |
| SCHEMBL30962647 | 0.86 | WEE1 (0.44) | TNK2LCKJAK3BTKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |