Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962793 | 0.96 | LCK (0.43) | LCKIRAK4IGF1RPDE4APDE4B | |
| SCHEMBL30962591 | 0.96 | LCK (0.43) | LCKIRAK4IGF1RPDE4APDE4B | |
| SCHEMBL30962959 | 0.93 | LCK (0.42) | LCKIRAK4IGF1RPDE4APDE4B | |
| SCHEMBL30962731 | 0.89 | SRC (0.44) | LCKIGF1RLRRK2SRCALK | |
| SCHEMBL30962709 | 0.88 | TNK2 (0.43) | LCKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30962871 | 0.86 | LCK (0.40) | LCKIGF1RLRRK2SRCALK | |
| SCHEMBL30962932 | 0.86 | LCK (0.40) | LCKIGF1RLRRK2SRCALK | |
| SCHEMBL30962746 | 0.84 | LCK (0.41) | LCKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30962900 | 0.84 | TTK (0.43) | LCKSRCALKMAP4K1KCNH2 | |
| SCHEMBL30962853 | 0.81 | TNK2 (0.48) | LCKIRAK4IRAK1SRCJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |