SCHEMBL30962731

SCHEMBL30962731

COc1nc(Nc2cc(C)ccc2O[C@@H]2CCN(C)C2)ncc1C(=O)Nc1c(Cl)cccc1Br

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 1/20 0.44
▸ TTK P33981 1/20 0.43
▸ PTK2 Q05397 13/20 0.43
▸ MAP4K1 Q92918 1/20 0.43
▸ INSR P06213 1/20 0.42
▸ IGF1R P08069 1/20 0.42
▸ ALK Q9UM73 1/20 0.42
▸ LCK P06239 2/20 0.42
▸ LRRK2 Q5S007 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30962900 0.90 TTK (0.43) SRCTTKPTK2MAP4K1ALK
SCHEMBL30962895 0.89 SRC (0.44) SRCTTKPTK2MAP4K1LCK
SCHEMBL30962748 0.89 SRC (0.44) SRCTTKPTK2MAP4K1LCK
SCHEMBL30962938 0.89 PTK2 (0.43) SRCPTK2MAP4K1LCK
SCHEMBL30962832 0.89 PTK2 (0.43) SRCPTK2MAP4K1LCK
SCHEMBL30962854 0.89 LCK (0.42) SRCTTKMAP4K1IGF1RALK
SCHEMBL30962793 0.87 LCK (0.43) SRCMAP4K1IGF1RLCKLRRK2
SCHEMBL30962591 0.87 LCK (0.43) SRCMAP4K1IGF1RLCKLRRK2
SCHEMBL30962929 0.85 SRC (0.46) SRCTTKMAP4K1LCK
SCHEMBL30962930 0.85 SRC (0.46) SRCTTKMAP4K1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642767-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS Acrivon Therapeutics, Inc. (US) 2025-11-05 — — EP disclosed
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