SCHEMBL30962820

SCHEMBL30962820

CCOc1nc(Nc2ccc(OC3CCN(C)CC3)c(C)c2)ncc1C(=O)Nc1c(Cl)cccc1Br

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 11/20 0.47
▸ TNK2 Q07912 2/20 0.45
▸ LCK P06239 1/20 0.45
▸ JAK3 P52333 1/20 0.45
▸ BTK Q06187 1/20 0.45
▸ HCK P08631 1/20 0.42
▸ FGFR1 P11362 1/20 0.42
▸ TTK P33981 1/20 0.42
▸ SIK1 P57059 2/20 0.41
▸ SIK2 Q9H0K1 2/20 0.41
▸ SIK3 Q9Y2K2 2/20 0.41
▸ EGFR P00533 2/20 0.40
▸ AXL P30530 1/20 0.40
▸ BRD4 O60885 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30962930 0.93 SRC (0.46) SRCTNK2LCKJAK3HCK
SCHEMBL30962929 0.93 SRC (0.46) SRCTNK2LCKJAK3HCK
SCHEMBL30962853 0.91 TNK2 (0.48) SRCTNK2LCKJAK3BTK
SCHEMBL30962666 0.90 JAK3 (0.42) SRCTNK2LCKJAK3BTK
SCHEMBL30962748 0.90 SRC (0.44) SRCLCKJAK3HCKFGFR1
SCHEMBL30962895 0.90 SRC (0.44) SRCLCKJAK3HCKFGFR1
SCHEMBL30962835 0.89 JAK3 (0.41) SRCTNK2LCKJAK3BTK
SCHEMBL30962900 0.89 TTK (0.43) SRCTNK2LCKJAK3BTK
SCHEMBL30962759 0.84 SRC (0.47) SRCLCKJAK3HCKFGFR1
SCHEMBL30962907 0.84 SRC (0.47) SRCLCKJAK3HCKFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642767-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS Acrivon Therapeutics, Inc. (US) 2025-11-05 — — EP disclosed
Send feedback