Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962666 | 0.96 | JAK3 (0.42) | JAK3LCKBTKTNK2IGF1R | |
| SCHEMBL30962749 | 0.94 | PIK3CD (0.43) | BTKIGF1REGFRPIK3CDSRC | |
| SCHEMBL30962655 | 0.90 | EGFR (0.42) | IGF1REGFRSRCCCNKCCNA2 | |
| SCHEMBL30962820 | 0.89 | SRC (0.47) | JAK3LCKBTKTNK2EGFR | |
| SCHEMBL30962853 | 0.84 | TNK2 (0.48) | JAK3LCKBTKTNK2EGFR | |
| SCHEMBL30962895 | 0.83 | SRC (0.44) | JAK3LCKEGFRSRC | |
| SCHEMBL30962748 | 0.83 | SRC (0.44) | JAK3LCKEGFRSRC | |
| SCHEMBL30962660 | 0.83 | IGF1R (0.44) | JAK3IGF1RSRCJAK2TP53 | |
| SCHEMBL30962735 | 0.83 | IGF1R (0.44) | JAK3IGF1RSRCJAK2TP53 | |
| SCHEMBL30962930 | 0.82 | SRC (0.46) | JAK3LCKTNK2EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |