Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15204972 | 0.83 | SMN1; SMN2 (0.50) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL8301115 | 0.83 | LMNA (0.54) | KMT2ASMN1; SMN2LMNANPC1CYP1A2 | |
| SCHEMBL9001643 | 0.79 | KMT2A (0.53) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL28154646 | 0.79 | LMNA (0.51) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL8341101 | 0.79 | LMNA (0.46) | KMT2ASMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL2485282 | 0.79 | SMN1; SMN2 (0.44) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL28867961 | 0.78 | GPBAR1 (0.50) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL14507079 | 0.78 | KMT2A (0.58) | KDM4EKMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL3088778 | 0.77 | GPBAR1 (0.46) | KMT2ASMN1; SMN2LMNAGPBAR1 | |
| SCHEMBL15221592 | 0.76 | KDM4E (0.43) | KDM4EKMT2ASMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799918-B2 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-09-21 | — | — | US | disclosed |
| US-7799918-B2 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-09-21 | — | — | US | disclosed |
| US-7799918-B2 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-09-21 | — | — | US | disclosed |
| US-20080214818-A1 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2008-09-04 | — | — | US | disclosed |
| US-20080214818-A1 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2008-09-04 | — | — | US | disclosed |
| US-20080214818-A1 | Organic metal complexes | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214818-A1 | Organic metal complexes | C5, C9, C1S | KDM4E 2302/4885KMT2A 1902/4885SMN1; SMN2 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.