Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 12/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963570 | 0.85 | POLB (0.37) | POLBMAPTTSHRGPX4TP53 | |
| SCHEMBL30963427 | 0.81 | POLB (0.35) | POLBMAPTTSHRGPX4TP53 | |
| SCHEMBL30963528 | 0.78 | GPX4 (0.38) | POLBMAPTGPX4TP53RXFP1 | |
| SCHEMBL31201073 | 0.78 | ALDH1A1 (0.36) | POLBMAPTTP53 | |
| SCHEMBL30963488 | 0.77 | GPX4 (0.37) | POLBMAPTGPX4TP53RXFP1 | |
| SCHEMBL30963611 | 0.77 | POLB (0.36) | POLBMAPTTP53RXFP1 | |
| SCHEMBL30963579 | 0.77 | POLB (0.33) | POLBMAPTTP53 | |
| SCHEMBL30963449 | 0.73 | POLB (0.41) | POLBMAPTTP53RXFP1 | |
| SCHEMBL31201096 | 0.72 | POLB (0.37) | POLBMAPTGPX4TP53RXFP1 | |
| SCHEMBL30963402 | 0.69 | ALDH1A1 (0.39) | POLBMAPTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651944-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-4638446-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024233767-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024137607-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-06-27 | — | — | WO | disclosed |