Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500726 | 1.00 | MAPT (0.74) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL22500248 | 0.86 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12359455 | 0.78 | NR1H4 (0.56) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1996378 | 0.77 | HCAR2 (0.60) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL13675936 | 0.77 | RAB9A (0.76) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7156743 | 0.75 | SMN1; SMN2 (1.00) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL22500570 | 0.75 | SMN1; SMN2 (0.76) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30964122 | 0.75 | ALDH1A1 (0.76) | MAPTALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7934478 | 0.75 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7090298 | 0.74 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | disclosed |