Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD5 | P21918 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097734 | 0.91 | GAA (0.62) | DRD2HTR2ADRD3DRD5MEN1 | |
| SCHEMBL23097663 | 0.84 | DRD2 (0.62) | DRD2HTR2ADRD3DRD4HTR1A | |
| SCHEMBL11285131 | 0.81 | DRD2 (0.69) | DRD2HTR2ASLC6A2SLC6A4HTR7 | |
| SCHEMBL23097735 | 0.80 | GAA (0.60) | DRD2HTR2ADRD3DRD4HTR1A | |
| SCHEMBL20512952 | 0.79 | DRD2 (1.00) | DRD2 | |
| SCHEMBL30179315 | 0.79 | DRD2 (1.00) | DRD2 | |
| SCHEMBL13532793 | 0.79 | DRD2 (0.82) | DRD2HTR2ADRD3DRD4DRD5 | |
| SCHEMBL23097721 | 0.78 | DRD2 (0.56) | DRD2HTR2ADRD3DRD4HTR1A | |
| SCHEMBL11262793 | 0.78 | RECQL (0.66) | DRD2HTR2AHTR7HRH1HRH3 | |
| SCHEMBL10665990 | 0.78 | DRD2 (1.00) | DRD2DRD3DRD4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |