Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285131 | 0.97 | DRD2 (0.69) | RECQLSMN1; SMN2DRD2HTR2AHTR7 | |
| SCHEMBL11268707 | 0.88 | SLC6A4 (0.65) | RECQLSMN1; SMN2DRD2HTR7HRH1 | |
| SCHEMBL11276701 | 0.86 | HRH1 (0.62) | DRD2HTR2AHTR7SIGMAR1HRH1 | |
| SCHEMBL11278314 | 0.85 | SLC6A4 (0.70) | RECQLSMN1; SMN2DRD2HTR7HRH1 | |
| SCHEMBL11284128 | 0.84 | HTR7 (0.59) | DRD2HTR2AHTR7SIGMAR1 | |
| SCHEMBL11219235 | 0.84 | HRH1 (0.80) | DRD2HTR2AHTR7SIGMAR1HRH1 | |
| SCHEMBL11278148 | 0.84 | KCNH2 (0.64) | DRD2HTR7HRH1HRH3 | |
| SCHEMBL11282280 | 0.84 | ADRA1D (0.70) | DRD2HTR7HRH1HRH3 | |
| SCHEMBL11276751 | 0.84 | HTR7 (0.58) | DRD2HTR2AHTR7SIGMAR1 | |
| SCHEMBL9121867 | 0.84 | DRD2 (0.63) | RECQLSMN1; SMN2DRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |