SCHEMBL30964513

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.64

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	13/20	0.64

▸	CALCR	P30988	13/20	0.64

▸	MAPK8	P45983	1/20	0.63

▸	MAPK9	P45984	1/20	0.63

▸	MAPK10	P53779	1/20	0.63

▸	NMUR2	Q9GZQ4	3/20	0.59

▸	NMUR1	Q9HB89	3/20	0.59

▸	KEAP1	Q14145	1/20	0.58

▸	APLNR	P35414	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30887974	0.93	KEAP1 (0.64)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30887975	0.92	KEAP1 (0.65)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30423109	0.92	APLNR (0.60)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30607401	0.90	NMUR2 (0.65)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30712950	0.89	MAPK8 (0.67)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL31182879	0.89	RAMP3 (0.61)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL31182992	0.88	NPY2R (0.66)	RAMP3CALCR
SCHEMBL30974066	0.88	NMUR2 (0.60)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL29827447	0.88	KEAP1 (0.62)	RAMP3CALCRKEAP1
SCHEMBL32670346	0.88	RAMP3 (0.64)	RAMP3CALCRNMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024085841-A1	A HUMANIN-LOADED SOLID LIPID NANOPARTICLE FOR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES AND A METHOD FOR PRODUCING THE HUMANIN-LOADED SOLID LIPID NANOPARTICLE	T.C ANKARA UNIVERSITESI REKTORLUGU BILIMSEL ARASTIRMA PROJELERI KOORDINASYON BIRIMI (TR)	2024-04-25	—	—	WO	disclosed