Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965262 | 0.95 | MEN1 (0.46) | S1PR5CYSLTR2CYSLTR1MEN1GAA | |
| SCHEMBL30965211 | 0.89 | ITGB3 (0.40) | S1PR5CYSLTR2CYSLTR1NAAAPPARG | |
| SCHEMBL30965266 | 0.84 | HPGD (0.46) | S1PR5CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL30965270 | 0.83 | HPGD (0.41) | S1PR5CYSLTR2CYSLTR1GAAHSD17B10 | |
| SCHEMBL30965222 | 0.82 | CYP19A1 (0.39) | S1PR5CYSLTR2CYSLTR1NAAASMN1; SMN2 | |
| SCHEMBL30965205 | 0.80 | ALDH1A1 (0.45) | S1PR5CYSLTR2CYSLTR1MEN1GAA | |
| SCHEMBL30965171 | 0.79 | HPGD (0.45) | S1PR5CYSLTR2CYSLTR1MEN1GAA | |
| SCHEMBL30965220 | 0.79 | S1PR5 (0.42) | S1PR5CYSLTR2CYSLTR1MEN1GAA | |
| SCHEMBL30965246 | 0.78 | AKR1B1 (0.47) | S1PR5CYSLTR2CYSLTR1MEN1GAA | |
| SCHEMBL30965269 | 0.75 | HSD17B10 (0.52) | S1PR5CYSLTR2CYSLTR1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125964-A | Isoindoline-1, 3-diketone mPGES-1 inhibitor and application thereof | 长江大学 | 2024-06-04 | — | — | CN | disclosed |