Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.70 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.61 |
| ▸ | INSR | P06213 | 2/20 | 0.61 |
| ▸ | IGF1R | P08069 | 2/20 | 0.61 |
| ▸ | FGFR3 | P22607 | 9/20 | 0.60 |
| ▸ | BRD4 | O60885 | 3/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965381 | 0.92 | EGFR (0.68) | EGFRALKINSRIGF1R | |
| SCHEMBL30965382 | 0.86 | ALK (0.82) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL28691226 | 0.83 | EGFR (1.00) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL29037794 | 0.82 | EGFR (0.65) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL30965394 | 0.81 | ALK (0.69) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL18912619 | 0.80 | FGFR3 (0.74) | EGFRFGFR3FGFR1FGFR2FGFR4 | |
| SCHEMBL22104574 | 0.80 | EGFR (0.75) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL30556273 | 0.80 | EGFR (0.75) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL25159176 | 0.80 | EGFR (0.63) | EGFRALKINSRIGF1RFGFR3 | |
| SCHEMBL30965380 | 0.79 | EGFR (0.67) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221696-A | Pyrimidine heterocyclic compound containing N-methylpiperazine structure, and preparation method and application thereof | 潍坊医学院 | 2024-06-21 | — | — | CN | disclosed |