SCHEMBL30965441

SCHEMBL30965441

Cc1cnc2nc(N)nc(N)c2n1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.53
PIK3CG P48736 3/20 0.50
NOS1 P29475 1/20 0.47
PIK3CA P42336 1/20 0.45
PIK3CB P42338 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63822 1.00 ADORA2A (0.53) ADORA2APIK3CGNOS1PIK3CAPIK3CB
Bromide SCHEMBL11633687 0.98 ADORA2A (0.52) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL12843982 0.84 ADORA1 (0.40) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL6239850 0.81 PIK3CG (0.41) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL3692533 0.79 ADORA2A (0.57) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL5514814 0.78 NOS1 (0.62) ADORA2ANOS1
SCHEMBL3537607 0.78 ADORA2A (0.55) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL3660280 0.76 ADORA2A (0.53) ADORA2APIK3CGNOS1PIK3CAPIK3CB
SCHEMBL8813993 0.76 NOS1 (0.61) NOS1
SCHEMBL12430387 0.76 ADORA2A (0.48) ADORA2APIK3CGNOS1PIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330110-A Method for determining 2, 4-diamino-7-chloromethyl pteridine 重庆药友制药有限责任公司 2024-07-12 CN disclosed