Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.39 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065469 | 1.00 | CYP19A1 (0.44) | CYP19A1BRD4MAPTALDH1A1KMT2A | |
| SCHEMBL24065461 | 0.89 | CYP19A1 (0.55) | CYP19A1BRD4MAPTALDH1A1KMT2A | |
| SCHEMBL30965469 | 0.89 | CYP19A1 (0.55) | CYP19A1BRD4MAPTALDH1A1KMT2A | |
| SCHEMBL30965487 | 0.82 | ALDH1A1 (0.43) | CYP19A1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL29241707 | 0.82 | ALDH1A1 (0.43) | CYP19A1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30965498 | 0.81 | MAPT (0.41) | BRD4MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL24065488 | 0.81 | MAPT (0.41) | BRD4MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL23292631 | 0.78 | MEN1 (0.46) | MAPTALDH1A1KMT2AMEN1HSPB1 | |
| SCHEMBL30965497 | 0.78 | MEN1 (0.46) | MAPTALDH1A1KMT2AMEN1HSPB1 | |
| SCHEMBL24065470 | 0.76 | MAPT (0.50) | BRD4MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |