Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29241707 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSPB1LMNACYP19A1ESPL1 | |
| SCHEMBL30965477 | 0.82 | CYP19A1 (0.44) | ALDH1A1HSPB1LMNACYP19A1MAPT | |
| SCHEMBL24065469 | 0.82 | CYP19A1 (0.44) | ALDH1A1HSPB1LMNACYP19A1MAPT | |
| SCHEMBL20303391 | 0.80 | LMNA (0.61) | ALDH1A1LMNACYP19A1MAPTMEN1 | |
| SCHEMBL14864874 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAESPL1MAPTMEN1 | |
| SCHEMBL28827186 | 0.73 | ALDH1A1 (0.54) | ALDH1A1LMNAESPL1MAPTMEN1 | |
| SCHEMBL22165621 | 0.73 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL30965497 | 0.72 | MEN1 (0.46) | ALDH1A1HSPB1MAPTMEN1KMT2A | |
| SCHEMBL23292631 | 0.72 | MEN1 (0.46) | ALDH1A1HSPB1MAPTMEN1KMT2A | |
| SCHEMBL4416673 | 0.71 | HSPB1 (0.59) | ALDH1A1HSPB1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |