Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065470 | 1.00 | MAPT (0.50) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL24065475 | 0.83 | MAPT (0.52) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL30965478 | 0.83 | MAPT (0.52) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL30965498 | 0.78 | MAPT (0.41) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL24065488 | 0.78 | MAPT (0.41) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL24065469 | 0.76 | CYP19A1 (0.44) | MAPTHTTMEN1KMT2ATSHR | |
| SCHEMBL30965477 | 0.76 | CYP19A1 (0.44) | MAPTHTTMEN1KMT2ATSHR | |
| SCHEMBL24065506 | 0.75 | KMT2A (0.46) | MAPTGAAUSP2HTTMEN1 | |
| SCHEMBL23292657 | 0.70 | NTRK1 (0.47) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30062086 | 0.70 | NTRK1 (0.47) | MAPTHTTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |