Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128555 | 0.87 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1GPR119MAPT | |
| SCHEMBL25225007 | 0.85 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1ALKTLR9 | |
| SCHEMBL30179902 | 0.85 | BACE1 (0.45) | ALKTLR9SMPD3GPR119GALR2 | |
| SCHEMBL24847590 | 0.85 | BACE1 (0.45) | ALKTLR9SMPD3GPR119GALR2 | |
| SCHEMBL15755156 | 0.85 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1GPR119MAPT | |
| SCHEMBL21999659 | 0.85 | MAPT (0.53) | SMARCA2SMARCA4PBRM1GPR119MAPT | |
| SCHEMBL31487397 | 0.81 | MAPT (0.52) | MAPTALDH1A1LMNAMEN1CYP1A2 | |
| SCHEMBL30965662 | 0.81 | MAPT (0.52) | MAPTALDH1A1LMNAMEN1CYP1A2 | |
| SCHEMBL29795685 | 0.81 | MAPT (0.54) | SMARCA2SMARCA4PBRM1GPR119MAPT | |
| SCHEMBL4130066 | 0.81 | MAPT (0.54) | SMARCA2SMARCA4PBRM1GPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |