Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487397 | 1.00 | MAPT (0.52) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL521293 | 0.89 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30258446 | 0.89 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL521504 | 0.88 | MAPT (0.59) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL24847590 | 0.81 | BACE1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2KCNH2 | |
| SCHEMBL30179902 | 0.81 | BACE1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2KCNH2 | |
| SCHEMBL30965619 | 0.81 | SMARCA2 (0.47) | MAPTALDH1A1LMNAMEN1CYP1A2 | |
| SCHEMBL2204635 | 0.81 | MAPT (0.53) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL2873860 | 0.80 | MAPT (0.55) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL22858566 | 0.80 | MAPT (0.52) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |