Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965538 | 0.88 | CHRM4 (0.45) | CHRM4HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL30965580 | 0.86 | CHRM4 (0.43) | CHRM4HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL30965621 | 0.85 | CHRM4 (0.39) | CHRM4MEN1KMT2ACHRM2 | |
| SCHEMBL30965560 | 0.81 | CHRM4 (0.59) | CHRM4HTR1ADRD2HTR2ACHRM2 | |
| SCHEMBL30965718 | 0.81 | CHRM4 (0.54) | CHRM4HTR1ADRD2HTR2ACHRM2 | |
| SCHEMBL30965585 | 0.81 | DDB1 (0.45) | DRD2 | |
| SCHEMBL30965827 | 0.80 | DDB1 (0.43) | DRD2 | |
| SCHEMBL30136056 | 0.79 | DDB1 (0.41) | CHRM4MEN1KMT2A | |
| SCHEMBL30965531 | 0.78 | DDB1 (0.47) | DRD2 | |
| SCHEMBL30981317 | 0.78 | DDB1 (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |