Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965617 | 0.87 | CA1 (0.38) | CHRM4ENPP2ATXN2CRBNDDB1 | |
| SCHEMBL30965634 | 0.85 | CHRM4 (0.50) | CHRM4MEN1KMT2ACHRM2 | |
| SCHEMBL30965642 | 0.83 | CHRM4 (0.44) | CHRM4ENPP2ATXN2MEN1KMT2A | |
| SCHEMBL30965622 | 0.82 | ENPP2 (0.37) | CHRM4ENPP2ATXN2CRBNDDB1 | |
| SCHEMBL31487782 | 0.82 | DRD4 (0.39) | CRBNDDB1 | |
| SCHEMBL30965519 | 0.82 | CHRM4 (0.42) | CHRM4ENPP2ATXN2TMEM97SIGMAR1 | |
| SCHEMBL30965709 | 0.82 | CRBN (0.41) | CRBNDDB1 | |
| SCHEMBL30135714 | 0.81 | ENPP2 (0.38) | CHRM4ENPP2ATXN2CRBNDDB1 | |
| SCHEMBL25819559 | 0.81 | ENPP2 (0.38) | CHRM4ENPP2ATXN2CRBNDDB1 | |
| SCHEMBL25819509 | 0.81 | CHRM4 (0.44) | CHRM4ENPP2ATXN2CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |