Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965560 | 0.85 | CHRM4 (0.59) | CHRM4DRD2HTR1AHTR2AVCP | |
| SCHEMBL30965519 | 0.84 | CHRM4 (0.42) | CHRM4DRD2VCPRORCCHRM2 | |
| SCHEMBL30965634 | 0.81 | CHRM4 (0.50) | CHRM4DRD2HTR1AHTR2AVCP | |
| SCHEMBL30965733 | 0.81 | CHRM4 (0.54) | CHRM4DRD2HTR1AHTR2A | |
| SCHEMBL30965817 | 0.79 | DRD2 (0.53) | CHRM4DRD2HTR1AHTR2AKCNA3 | |
| SCHEMBL30965686 | 0.78 | CHRM4 (0.53) | CHRM4DRD2HTR1AHTR2A | |
| SCHEMBL25666815 | 0.78 | F10 (0.41) | CHRM4CHRM2 | |
| SCHEMBL30965749 | 0.77 | CHRM4 (0.50) | CHRM4DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL30965830 | 0.77 | CHRM4 (0.49) | CHRM4DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL30965559 | 0.76 | CHRM4 (0.51) | CHRM4DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |