Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135765 | 0.94 | CRBN (0.43) | CRBNDDB1DRD2DRD3HDAC8 | |
| SCHEMBL25024163 | 0.94 | CRBN (0.43) | CRBNDDB1DRD2DRD3HDAC8 | |
| SCHEMBL30965660 | 0.92 | DRD2 (0.40) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL31712320 | 0.92 | CRBN (0.46) | CRBNDDB1DRD2DRD3HDAC8 | |
| SCHEMBL30965682 | 0.90 | CRBN (0.42) | CRBNDDB1DRD2HDAC8ESR1 | |
| SCHEMBL30981399 | 0.89 | DRD2 (0.53) | CRBNDDB1DRD2DRD3 | |
| SCHEMBL24753559 | 0.86 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL31334275 | 0.86 | CRBN (0.46) | CRBNDDB1DRD2DRD3 | |
| SCHEMBL30915142 | 0.86 | CRBN (0.49) | CRBNDDB1DRD2DRD3HDAC8 | |
| SCHEMBL30135859 | 0.85 | CRBN (0.41) | CRBNDDB1DRD2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |