Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965684 | 0.93 | DRD2 (0.39) | DRD2DDB1CRBN | |
| SCHEMBL30965669 | 0.92 | CRBN (0.43) | DRD2DRD3DDB1CRBNESR1 | |
| SCHEMBL30965799 | 0.92 | DRD2 (0.44) | DRD2DRD3DDB1CRBN | |
| SCHEMBL30965792 | 0.88 | CRBN (0.41) | DRD2DRD3DDB1CRBN | |
| SCHEMBL25024163 | 0.86 | CRBN (0.43) | DRD2DRD3DDB1CRBN | |
| SCHEMBL30135765 | 0.86 | CRBN (0.43) | DRD2DRD3DDB1CRBN | |
| SCHEMBL30965703 | 0.85 | CRBN (0.42) | DRD2DRD3DDB1CRBN | |
| SCHEMBL30965688 | 0.85 | CRBN (0.39) | DRD2DDB1CRBN | |
| SCHEMBL31487492 | 0.84 | DRD4 (0.39) | DRD2DRD3DDB1CRBN | |
| SCHEMBL30965552 | 0.84 | CRBN (0.43) | DRD2DRD3DDB1CRBNESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |