Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965766 | 0.92 | DRD2 (0.54) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL30965752 | 0.87 | MAPT (0.55) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL30965805 | 0.87 | DRD2 (0.45) | DRD2 | |
| SCHEMBL6335663 | 0.85 | MAPT (0.56) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL30965527 | 0.84 | MAPT (0.50) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1815044 | 0.82 | MAPT (0.61) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL5652480 | 0.81 | MAPT (0.58) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL3702193 | 0.80 | MAPT (0.56) | MAPTALDH1A1LMNADRD2POLB | |
| SCHEMBL30981439 | 0.80 | DRD2 (0.58) | MAPTALDH1A1LMNADRD2SMN1; SMN2 | |
| SCHEMBL21786064 | 0.80 | MAPT (0.75) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |