Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965766 | 0.89 | DRD2 (0.54) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL30965702 | 0.87 | MAPT (0.52) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL30981132 | 0.87 | MAPT (0.56) | MAPTALDH1A1LMNAHTR1AKMT2A | |
| SCHEMBL6335663 | 0.86 | MAPT (0.56) | MAPTALDH1A1LMNASMN1; SMN2SIRT6 | |
| SCHEMBL30965804 | 0.85 | DRD2 (0.43) | MAPTALDH1A1KMT2ASMN1; SMN2DRD2 | |
| SCHEMBL4822596 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1LMNAHTR1AKMT2A | |
| SCHEMBL30738841 | 0.81 | MAPT (0.54) | MAPTALDH1A1LMNAHTR1AKMT2A | |
| SCHEMBL1815044 | 0.79 | MAPT (0.61) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL27624491 | 0.78 | MAPT (0.57) | MAPTALDH1A1LMNASMN1; SMN2SIRT6 | |
| SCHEMBL4823574 | 0.78 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |