Sugi Predict

Sugi Predict / Compounds / SCHEMBL30965711

SCHEMBL30965711

SCHEMBL30965711

CCCCOC(=O)NN1CCC(CCN2CCN(c3cc(OC)c(C4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.39
▸ DRD2 P14416 11/20 0.37
▸ DRD3 P35462 11/20 0.37
▸ DRD4 P21917 10/20 0.37
▸ HTR1A P08908 2/20 0.37
▸ HTR2B P41595 2/20 0.37
▸ CRBN Q96SW2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965638 0.91 ESR1 (0.40) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL30965691 0.84 CRBN (0.41) ESR1DRD2DRD3DRD4CRBN
SCHEMBL30965600 0.83 ESR1 (0.41) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL30981086 0.83 DRD2 (0.39) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL30135862 0.82 CRBN (0.37) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL30135791 0.82 CRBN (0.43) ESR1DRD2CRBN
SCHEMBL30965673 0.82 HTT (0.43) CRBN
SCHEMBL30965629 0.78 CRBN (0.38) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL30965677 0.78 CRBN (0.43) ESR1DRD2DRD3DRD4HTR1A
SCHEMBL25031063 0.76 CRBN (0.45) ESR1DRD2DRD3DRD4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658658-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2025-12-10 — — EP disclosed
WO-2024162828-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2024-08-08 — — WO disclosed