SCHEMBL30965751

SCHEMBL30965751

NC1CC2(CCN(CCC3CCN(c4ccc(NC5CCC(=O)NC5=O)cc4F)CC3)CC2)C1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.42
CRBN Q96SW2 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31376445 0.92 DDB1 (0.43) DDB1CRBN
SCHEMBL30965688 0.91 CRBN (0.39) DDB1CRBN
SCHEMBL30915126 0.91 DDB1 (0.46) DDB1CRBN
SCHEMBL30981351 0.87 DDB1 (0.48) DDB1CRBN
SCHEMBL29179898 0.85 DDB1 (0.48) DDB1CRBN
SCHEMBL30981066 0.85 DDB1 (0.48) DDB1CRBN
SCHEMBL30981234 0.85 DDB1 (0.48) DDB1CRBN
SCHEMBL30965669 0.85 CRBN (0.43) DDB1CRBN
SCHEMBL31334104 0.83 CRBN (0.43) DDB1CRBN
SCHEMBL24125518 0.83 DDB1 (0.55) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658658-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2025-12-10 EP disclosed
WO-2024162828-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2024-08-08 WO disclosed