Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965751 | 0.92 | DDB1 (0.42) | DDB1CRBN | |
| SCHEMBL31333703 | 0.90 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL30965761 | 0.90 | CRBN (0.40) | DDB1CRBN | |
| SCHEMBL25024658 | 0.89 | CRBN (0.40) | DDB1CRBN | |
| SCHEMBL27225161 | 0.87 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL25023294 | 0.86 | DDB1 (0.57) | DDB1CRBN | |
| SCHEMBL30905890 | 0.86 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL31447643 | 0.86 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL29179902 | 0.85 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL30965709 | 0.85 | CRBN (0.41) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101025-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2025-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101025-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | PLK1, BUB1B, BUB1 | DDB1 132/4885CRBN 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.