SCHEMBL30966733

SCHEMBL30966733

COC(=O)c1cc(NC[C@@H]2CCO2)c(NC(=O)Cc2cc(F)c(Br)cc2F)c(OC)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.36
▸ KMT2A Q03164 3/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.34
▸ ALDH1A1 P00352 4/20 0.33
▸ LMNA P02545 2/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ ERBB2 P04626 1/20 0.33
▸ EPHA2 P29317 1/20 0.33
▸ EPHB4 P54760 1/20 0.33
▸ USP2 O75604 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ROCK2 O75116 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ KDM4E B2RXH2 3/20 0.32
▸ MAPT P10636 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27255582 1.00 HPGD (0.36) HPGDKMT2ARXFP1ALDH1A1LMNA
SCHEMBL30966736 0.91 MAPT (0.32) HPGDKMT2AALDH1A1LMNAL3MBTL1
SCHEMBL27255597 0.91 MAPT (0.32) HPGDKMT2AALDH1A1LMNAL3MBTL1
SCHEMBL22527749 0.85 ALDH1A1 (0.38) HPGDKMT2AALDH1A1LMNAUSP2
SCHEMBL31436768 0.85 ALDH1A1 (0.38) HPGDKMT2AALDH1A1LMNAUSP2
SCHEMBL27255581 0.83 ALDH1A1 (0.39) ALDH1A1LMNAL3MBTL1USP2TSHR
SCHEMBL27117337 0.76 KMT2A (0.39) HPGDKMT2AALDH1A1L3MBTL1TSHR
SCHEMBL27117333 0.76 KMT2A (0.39) HPGDKMT2AALDH1A1L3MBTL1TSHR
SCHEMBL31159930 0.76 KMT2A (0.37) HPGDKMT2AALDH1A1ROCK2NPSR1
SCHEMBL30808478 0.75 KMT2A (0.39) HPGDKMT2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619098-A1 GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS Eli Lilly and Company (US) 2025-09-24 — — EP disclosed
WO-2024107781-A1 GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2024-05-23 — — WO disclosed
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