Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | SCD | O00767 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325910 | 0.87 | SMN1; SMN2 (0.93) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL30309564 | 0.85 | HDAC6 (0.65) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL1691995 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL4726981 | 0.81 | KDM4E (0.80) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| Zolimidine SCHEMBL932657 | 0.80 | HDAC6 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL10648324 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL13325899 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL4727102 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL4727165 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL972809 | 0.80 | NPC1 (1.00) | SMN1; SMN2TP53NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184664-A | Synthetic method of naphtho [1',2', 4,5] imidazo [1,2-a ] pyridine fluorescent compound | 阜阳师范大学 | 2024-06-14 | — | — | CN | disclosed |