Lithium

Lithium

SCHEMBL30967321

C#Cc1cccc2ccccc12.[Li]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.46
CYP2A6 P11509 3/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 5/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CHAT P28329 1/20 0.42
HPGD P15428 3/20 0.41
CYP3A4 P08684 2/20 0.41
KEAP1 Q14145 1/20 0.41
HPRT1 P00492 1/20 0.40
GRM5 P41594 1/20 0.39
ABCB11 O95342 1/20 0.38
NR3C1 P04150 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ALOX15 P16050 1/20 0.38
ADRA2C P18825 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549980 0.98 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2ALDH1A1
SCHEMBL186670 0.98 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2ALDH1A1
SCHEMBL29977314 0.98 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2ALDH1A1
Methane SCHEMBL28604850 0.95 CYP1A2 (0.46) CYP1A2CYP2A6CA1CA2ALDH1A1
Biphenyl SCHEMBL28003550 0.89 CYP2A6 (0.41) CYP1A2CYP2A6CA1CA2ALDH1A1
SCHEMBL1933777 0.85 HPRT1 (0.58) CYP1A2CYP2A6CA1CA2ALDH1A1
SCHEMBL29291198 0.82 SLC6A4 (0.42) CYP1A2CYP2A6CA1CA2ALDH1A1
SCHEMBL6894903 0.82 FABP7 (0.39) CYP1A2CYP2A6CA1CA2ALDH1A1
Phthalic Anhydride SCHEMBL28434150 0.81 ALOX15 (0.48) CA1CA2ALDH1A1TDP1HPGD
SCHEMBL25212172 0.80 CYP2A6 (0.41) CYP1A2CYP2A6CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369114-B Method for preparing benzogermanium pyrrole compound by inducing intramolecular cyclization reaction by using lithium naphthalide, product and application 杭州师范大学 2024-06-25 CN disclosed