SCHEMBL6894903

SCHEMBL6894903

C#Cc1cccc2c(C#C)cccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.39
FABP3 P05413 1/20 0.39
FABP5 Q01469 1/20 0.39
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 3/20 0.38
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP19A1 P11511 1/20 0.31
DYRK1A Q13627 1/20 0.30
PLA2G7 Q13093 1/20 0.30
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5179481 0.88 IMPDH2 (0.37) FABP7FABP3FABP5CYP1A2CYP2A6
SCHEMBL689722 0.85 ALDH1A1 (0.59) FABP7FABP3FABP5CYP1A2ALDH1A1
SCHEMBL29977677 0.85 IDO1 (0.46) FABP7FABP3FABP5CYP1A2CA1
SCHEMBL29977311 0.85 ALDH1A1 (0.59) FABP7FABP3FABP5CYP1A2ALDH1A1
SCHEMBL29549980 0.84 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2CYP1B1
SCHEMBL29977314 0.84 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2CYP1B1
SCHEMBL186670 0.84 CYP1A2 (0.48) CYP1A2CYP2A6CA1CA2CYP1B1
Lithium SCHEMBL30967321 0.82 CYP1A2 (0.46) CYP1A2CYP2A6CA1CA2CYP1B1
Methane SCHEMBL28604850 0.82 CYP1A2 (0.46) CYP1A2CYP2A6CA1CA2CYP1B1
SCHEMBL1933777 0.82 HPRT1 (0.58) CYP1A2CYP2A6CA1CA2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6795230-B1 Self-assembled molecular color switch HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-09-21 US disclosed