Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.35 |
| ▸ | MDM4 | O15151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967506 | 0.81 | TRPV4 (0.31) | — | |
| SCHEMBL30967507 | 0.81 | TRPV4 (0.31) | — | |
| SCHEMBL30967480 | 0.79 | TRPV4 (0.33) | — | |
| SCHEMBL30967635 | 0.76 | GPR119 (0.30) | — | |
| SCHEMBL30967476 | 0.75 | MDM2 (0.32) | MDM2TLR2TLR1HDAC1HDAC2 | |
| SCHEMBL30967457 | 0.74 | SYK (0.43) | — | |
| SCHEMBL29763156 | 0.70 | MDM2 (0.54) | MDM2MDM4TP53TLR2 | |
| SCHEMBL12346100 | 0.70 | MDM2 (0.54) | MDM2MDM4TP53TLR2 | |
| SCHEMBL18795320 | 0.70 | MDM2 (0.54) | MDM2MDM4TP53TLR2 | |
| SCHEMBL30967546 | 0.69 | DYRK1A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |