Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967538 | 0.90 | CACNA2D1 (0.32) | STAT3HDAC1HDAC8HDAC6CACNA2D1 | |
| SCHEMBL30967472 | 0.88 | — | — | |
| SCHEMBL30967492 | 0.85 | HDAC1 (0.31) | HDAC1HDAC8HDAC6CACNA2D1 | |
| SCHEMBL30967660 | 0.85 | HDAC1 (0.31) | HDAC1HDAC8HDAC6 | |
| SCHEMBL30967622 | 0.85 | HDAC1 (0.31) | HDAC1HDAC8HDAC6 | |
| SCHEMBL30967475 | 0.85 | DRD3 (0.39) | STAT3HDAC1HDAC8HDAC6 | |
| SCHEMBL30967641 | 0.83 | KIFC1 (0.31) | — | |
| SCHEMBL30967470 | 0.82 | CYP1A2 (0.39) | — | |
| SCHEMBL30967560 | 0.81 | SCARB1 (0.34) | CACNA2D1 | |
| SCHEMBL30967584 | 0.81 | SCARB1 (0.35) | CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |