Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967456 | 0.91 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2ATP53 | |
| SCHEMBL30967629 | 0.91 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2ATP53 | |
| SCHEMBL30967686 | 0.87 | KIFC1 (0.35) | DRD3KIFC1HDAC4HDAC7HDAC8 | |
| SCHEMBL30967523 | 0.85 | STAT3 (0.31) | HDAC8HDAC6STAT3HDAC1 | |
| SCHEMBL30967460 | 0.81 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967608 | 0.81 | DRD3 (0.46) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967687 | 0.81 | KIFC1 (0.47) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967528 | 0.78 | KIFC1 (0.39) | DRD3KIFC1HDAC4HDAC7HDAC8 | |
| SCHEMBL30967538 | 0.78 | CACNA2D1 (0.32) | DRD3DRD2HDAC8HDAC6STAT3 | |
| SCHEMBL30967529 | 0.75 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |