Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 8/20 | 0.55 |
| ▸ | CTSK | P43235 | 8/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227553 | 0.92 | SYK (0.62) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL6241676 | 0.88 | SYK (0.61) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL25022113 | 0.88 | SYK (0.57) | SYKMAPT | |
| SCHEMBL27696907 | 0.87 | CTSS (0.57) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL5044640 | 0.87 | SYK (0.60) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL19934131 | 0.86 | SYK (0.61) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL1022494 | 0.86 | SYK (0.65) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL17841824 | 0.86 | SYK (0.65) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL606625 | 0.86 | SYK (0.65) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL14842312 | 0.85 | SYK (0.64) | SYKCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |