Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 8/20 | 0.56 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967604 | 0.92 | SYK (0.58) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL19934131 | 0.92 | SYK (0.61) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL27696907 | 0.90 | CTSS (0.57) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL6241676 | 0.89 | SYK (0.61) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL25022113 | 0.89 | SYK (0.57) | SYKMAPT | |
| SCHEMBL30902907 | 0.88 | MAPT (0.65) | CTSKCTSSMAPTKLK7KLK5 | |
| SCHEMBL20364114 | 0.88 | LMNA (0.57) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL5044640 | 0.88 | SYK (0.60) | SYKCTSKCTSSMAPTCTSL | |
| SCHEMBL6482274 | 0.88 | CTSS (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL17841824 | 0.87 | SYK (0.65) | SYKCTSKCTSSMAPTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355041-B1 | Complex porphyrine compounds substituted in position 13,17 by propionic acid and propionic-acid derivatives, process for their preparation and pharmaceutical compositions containing same | SCHERING AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| US-5275801-A | X-ray and magnetic resonance imaging of tumors | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0355041-A2 | Complex porphyrine compounds substituted in position 13,17 by propionic acid and propionic-acid derivatives, process for their preparation and pharmaceutical compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-02-21 | — | — | EP | disclosed |