Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | KIFC1 | Q9BW19 | 9/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967687 | 0.93 | KIFC1 (0.47) | DRD3KIFC1DRD2HTR2AAURKA | |
| SCHEMBL30967456 | 0.90 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967460 | 0.90 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2AAURKA | |
| SCHEMBL30967629 | 0.90 | DRD3 (0.44) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967545 | 0.86 | DRD3 (0.46) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967560 | 0.85 | SCARB1 (0.34) | DRD3CACNA2D1HTR1DSLC6A4 | |
| SCHEMBL30967475 | 0.81 | DRD3 (0.39) | DRD3KIFC1DRD2HTR2AKCNH2 | |
| SCHEMBL30967571 | 0.80 | KIFC1 (0.41) | DRD3KIFC1 | |
| SCHEMBL30967584 | 0.78 | SCARB1 (0.35) | DRD3KIFC1CACNA2D1HTR1DSLC6A4 | |
| SCHEMBL30967528 | 0.78 | KIFC1 (0.39) | DRD3KIFC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |