Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640463 | 1.00 | SLC6A4 (0.51) | SLC6A4SLC6A3TSHRNPSR1HDAC4 | |
| SCHEMBL22945326 | 0.89 | SLC6A4 (0.43) | SLC6A4SLC6A3TSHRNPSR1HDAC4 | |
| SCHEMBL23380763 | 0.83 | SLC6A4 (0.45) | SLC6A4SLC6A3TSHRNPSR1HDAC4 | |
| SCHEMBL21512715 | 0.82 | GRIN2B (0.42) | SLC6A3 | |
| SCHEMBL21512714 | 0.82 | OPRK1 (0.43) | HDAC4ALDH1A1LMNADRD4KMT2A | |
| SCHEMBL29969542 | 0.82 | OPRK1 (0.43) | HDAC4ALDH1A1LMNADRD4KMT2A | |
| SCHEMBL29969842 | 0.82 | GRIN2B (0.42) | SLC6A3 | |
| SCHEMBL18640459 | 0.82 | POLB (0.40) | SLC6A4SLC6A3TSHRALDH1A1POLB | |
| SCHEMBL30015707 | 0.81 | KDM1A (0.51) | TSHRNPSR1HDAC4KDM1ARCOR1 | |
| SCHEMBL15192136 | 0.81 | SLC6A3 (0.48) | SLC6A4SLC6A3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |