Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 6/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237285 | 0.91 | PRKAB2 (0.33) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30217366 | 0.91 | PRKAB2 (0.33) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29237313 | 0.86 | TRPA1 (0.33) | RHEBTRPA1 | |
| SCHEMBL29237546 | 0.86 | TRPA1 (0.33) | RHEBTRPA1 | |
| SCHEMBL30217023 | 0.86 | TRPA1 (0.33) | RHEBTRPA1 | |
| SCHEMBL30217329 | 0.86 | TRPA1 (0.33) | RHEBTRPA1 | |
| SCHEMBL31065875 | 0.85 | PRKAB2 (0.41) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL31110793 | 0.83 | AURKA (0.34) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30967927 | 0.83 | AKR1C3 (0.43) | KDM4EPOLB | |
| SCHEMBL30840391 | 0.83 | PRKAB2 (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |