Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237550 | 1.00 | DGAT2 (0.34) | DGAT2CDK8CNR2DNMT3BVDR | |
| SCHEMBL30216993 | 1.00 | DGAT2 (0.34) | DGAT2CDK8CNR2DNMT3BVDR | |
| SCHEMBL29237854 | 0.92 | FFAR1 (0.33) | CDK8CNR2HPGDS | |
| SCHEMBL30967895 | 0.92 | FFAR1 (0.33) | CDK8CNR2HPGDS | |
| SCHEMBL30217039 | 0.92 | FFAR1 (0.33) | CDK8CNR2HPGDS | |
| SCHEMBL30217199 | 0.84 | CDK8 (0.33) | CDK8CNR2DNMT3BVDRPPARD | |
| SCHEMBL30967953 | 0.84 | FFAR1 (0.32) | — | |
| SCHEMBL30217298 | 0.84 | FFAR1 (0.32) | — | |
| SCHEMBL30217364 | 0.83 | CDK8 (0.32) | CDK8CNR2DNMT3BVDRPPARD | |
| SCHEMBL30217287 | 0.83 | DGAT2 (0.34) | DGAT2CDK8DNMT3BVDRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |