Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 5/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217297 | 0.94 | FFAR4 (0.34) | CDK8BACE1BACE2 | |
| SCHEMBL30217199 | 0.92 | CDK8 (0.33) | CDK8DNMT3BBACE1BACE2VDR | |
| SCHEMBL30217154 | 0.85 | CNR2 (0.33) | CDK8DNMT3BBACE1BACE2VDR | |
| SCHEMBL29237550 | 0.83 | DGAT2 (0.34) | CDK8DNMT3BVDRPPARDKDM4E | |
| SCHEMBL30216993 | 0.83 | DGAT2 (0.34) | CDK8DNMT3BVDRPPARDKDM4E | |
| SCHEMBL30967875 | 0.83 | DGAT2 (0.34) | CDK8DNMT3BVDRPPARDKDM4E | |
| SCHEMBL29237349 | 0.83 | FFAR1 (0.32) | — | |
| SCHEMBL30217224 | 0.83 | FFAR1 (0.32) | — | |
| SCHEMBL30217316 | 0.81 | ADORA2B (0.34) | DNMT3BBACE1BACE2 | |
| SCHEMBL30217105 | 0.81 | CYP4F2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |