Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967884 | 1.00 | CTSB (0.40) | CTSBCTSSCTSKHSP90AA1HSP90AB1 | |
| SCHEMBL30967908 | 0.78 | L3MBTL1 (0.42) | HSP90AA1HSP90AB1NR1H2 | |
| SCHEMBL29237478 | 0.78 | L3MBTL1 (0.42) | HSP90AA1HSP90AB1NR1H2 | |
| SCHEMBL30217202 | 0.76 | TTR (0.42) | MAOB | |
| SCHEMBL29237424 | 0.76 | TTR (0.42) | MAOB | |
| SCHEMBL29237420 | 0.76 | TTR (0.42) | MAOB | |
| SCHEMBL30918979 | 0.75 | HSP90AA1 (0.49) | CTSBCTSSCTSKHSP90AA1HSP90AB1 | |
| SCHEMBL445394 | 0.75 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1PIK3R1PIK3CANR1H2 | |
| SCHEMBL2628927 | 0.75 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1PIK3R1PIK3CANR1H2 | |
| SCHEMBL445392 | 0.75 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1PIK3R1PIK3CANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |