Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14309739 | 0.80 | CYP1A2 (0.44) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL16685781 | 0.80 | CYP2D6 (0.39) | LMNACYP2D6CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL29244675 | 0.77 | CYP2D6 (0.37) | LMNACYP2D6CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL30967989 | 0.77 | CYP2D6 (0.40) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30967990 | 0.77 | CYP2D6 (0.38) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20030746 | 0.77 | CYP2D6 (0.35) | MAPTCYP2D6CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL30968041 | 0.77 | LMNA (0.42) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30935953 | 0.77 | CYP2D6 (0.35) | MAPTCYP2D6CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL24175503 | 0.74 | TERT (0.41) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL15425314 | 0.74 | LMNA (0.46) | LMNAMAPTCYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |