SCHEMBL30968014 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TLR8	Q9NR97	12/20	0.42

▸	TLR7	Q9NYK1	4/20	0.33

▸	TLR9	Q9NR96	3/20	0.33

▸	TLR4	O00206	2/20	0.33

▸	MAPK1	P28482	1/20	0.32

▸	HSD17B10	Q99714	1/20	0.32

▸	L3MBTL1	Q9Y468	1/20	0.32

▸	IRAK4	Q9NWZ3	3/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20134852	0.69	TLR8 (0.60)	TLR8TLR7TLR9TLR4IRAK4
Hydrochloric Acid SCHEMBL28215651	0.68	TLR8 (0.59)	TLR8TLR7TLR9TLR4IRAK4
SCHEMBL31065773	0.68	SUV39H2 (0.34)	IRAK4
SCHEMBL31065746	0.67	MAPK1 (0.31)	MAPK1HSD17B10L3MBTL1
SCHEMBL31065802	0.66	SMN1; SMN2 (0.40)	MAPK1HSD17B10L3MBTL1
SCHEMBL31065797	0.66	SMN1; SMN2 (0.40)	MAPK1HSD17B10L3MBTL1
SCHEMBL20135691	0.65	TLR8 (0.57)	TLR8TLR7TLR9TLR4IRAK4
SCHEMBL20135108	0.65	TLR8 (0.57)	TLR8TLR7TLR9TLR4IRAK4
SCHEMBL31065794	0.64	SMN1; SMN2 (0.38)	MAPK1HSD17B10L3MBTL1
SCHEMBL31065753	0.64	KAT2B (0.33)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118239959-A	Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof	上海深势唯思科技有限责任公司	2024-06-25	—	—	CN	disclosed