Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968032 | 0.76 | CHRM2 (0.43) | SUV39H2CHRM2CHRM1CHRM3JAK1 | |
| SCHEMBL31065752 | 0.74 | GPR119 (0.35) | SUV39H2CHRM1GPR119 | |
| SCHEMBL31065759 | 0.73 | KAT2B (0.33) | CHRM2CHRM1CHRM3JAK1GPR119 | |
| SCHEMBL31065753 | 0.73 | KAT2B (0.33) | CHRM2CHRM1CHRM3JAK1GPR119 | |
| SCHEMBL31065776 | 0.73 | GPR119 (0.32) | CHRM2CHRM1CHRM3JAK1GPR119 | |
| SCHEMBL31065748 | 0.72 | USP30 (0.32) | CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL31065750 | 0.72 | GPR119 (0.32) | GPR119 | |
| SCHEMBL31065757 | 0.72 | JAK2 (0.34) | CHRM1JAK1GPR119 | |
| SCHEMBL30968014 | 0.68 | TLR8 (0.42) | IRAK4 | |
| SCHEMBL31424049 | 0.65 | KDM4E (0.44) | JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |