Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | PAK4 | O96013 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065802 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL31065794 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL31065761 | 0.78 | PLD3 (0.35) | SMN1; SMN2KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL30968139 | 0.75 | DHODH (0.35) | SMN1; SMN2KDM4EKMT2AKDM1A | |
| SCHEMBL31065793 | 0.73 | CSNK2A1 (0.35) | SMN1; SMN2KDM4EMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL31065767 | 0.71 | FASN (0.35) | SMN1; SMN2L3MBTL1KMT2AALDH1A1MAOA | |
| SCHEMBL30968033 | 0.70 | SYK (0.33) | SMN1; SMN2KDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL30968081 | 0.68 | KARS1 (0.36) | SMN1; SMN2HTTMAPTMAOA | |
| SCHEMBL22740095 | 0.65 | SLC9A1 (0.53) | KDM4EL3MBTL1ALDH1A1MAPTHRH3 | |
| SCHEMBL30968088 | 0.64 | SPR (0.38) | SMN1; SMN2KDM4EPAK4ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |